This Conference Report summarises a Wellcome Trust-sponsored symposium held at the 13th World Congress of the International Association of Bioethics, held in Edinburgh 14-17 June 2016 (IAB2016). This symposium was curated by the Liminal Spaces Project, which is conducted under the auspices of the JK Mason Institute for Medicine, Life Sciences and the Law at the University of Edinbugh School of Law, and sought to address the question: “What does it mean to regulate in the public interest?”