3.6.5.2 Small monomeric GTPases in GtoPdb v.2024.2

Authors

DOI:

https://doi.org/10.2218/gtopdb/F896/2024.2

Abstract

Small G-proteins, are a family of hydrolase enzymes that can bind and hydrolyze guanosine triphosphate (GTP). They are a type of G-protein found in the cytosol that are homologous to the alpha subunit of heterotrimeric G-proteins, but unlike the alpha subunit of G proteins, a small GTPase can function independently as a hydrolase enzyme to bind to and hydrolyze a guanosine triphosphate (GTP) to form guanosine diphosphate (GDP). The best-known members are the Ras GTPases and hence they are sometimes called Ras subfamily GTPases.

Published

26-Jun-2024

Issue

Section

Summaries

How to Cite

“3.6.5.2 Small monomeric GTPases in GtoPdb v.2024.2” (2024) IUPHAR/BPS Guide to Pharmacology CITE, 2024(2). doi:10.2218/gtopdb/F896/2024.2.