3C. 3-Ketosteroid receptors in GtoPdb v.2023.1

Authors

  • Derek Cain National Institutes of Health
  • John Cidlowski National Institutes of Health https://orcid.org/0000-0003-1420-0516
  • Dean P. Edwards Baylor College of Medicine
  • Peter Fuller Hudson Instiitute of Medical Research
  • Sandra L. Grimm Baylor College of Medicine
  • Sean Hartig Baylor College of Medicine
  • Carol A. Lange University of Minnesota
  • Robert H. Oakley National Institutes of Health
  • Jennifer K. Richer University of Colorado
  • Carol A. Sartorius University of Colorado
  • Marc Tetel Wellesley College
  • Nancy Weigel Baylor College of Medicine
  • Morag J. Young Baker Heart and Diabetes Institute

DOI:

https://doi.org/10.2218/gtopdb/F98/2023.1

Abstract

Steroid hormone receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Nuclear Hormone Receptors [75, 218, 3]) are nuclear hormone receptors of the NR3 class, with endogenous agonists that may be divided into 3-hydroxysteroids (estrone and 17β-estradiol) and 3-ketosteroids (dihydrotestosterone [DHT], aldosterone, cortisol, corticosterone, progesterone and testosterone). For rodent GR and MR, the physiological ligand is corticosterone rather than cortisol.

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Published

26-Apr-2023

How to Cite

Cain, D. (2023) “3C. 3-Ketosteroid receptors in GtoPdb v.2023.1”, IUPHAR/BPS Guide to Pharmacology CITE, 2023(1). doi: 10.2218/gtopdb/F98/2023.1.

Issue

Vol. 2023 No. 1 (2023)

Section

Summaries