Kisspeptin receptor in GtoPdb v.2023.1

Anthony P. Davenport; Janet J. Maguire; Edward J. Mead; Adam J Pawson

doi:10.2218/gtopdb/F34/2023.1

Authors

Anthony P. Davenport University of Cambridge https://orcid.org/0000-0002-2096-3117
Janet J. Maguire University of Cambridge https://orcid.org/0000-0002-9254-7040
Edward J. Mead University of Cambridge
Adam J Pawson The University of Edinburgh https://orcid.org/0000-0003-2280-845X

DOI:

https://doi.org/10.2218/gtopdb/F34/2023.1

Abstract

The kisspeptin receptor (nomenclature as agreed by the NC-IUPHAR Subcommittee on the kisspeptin receptor [11]), like neuropeptide FF (NPFF), prolactin-releasing peptide (PrP) and QRFP receptors (provisional nomenclature) responds to endogenous peptides with an arginine-phenylalanine-amide (RFamide) motif. kisspeptin-54 (KP54, originally named metastin), kisspeptin-13 (KP13) and kisspeptin-10 (KP10) are biologically-active peptides cleaved from the KISS1 (Q15726) gene product. Kisspeptins have roles in, for example, cancer metastasis, fertility/puberty regulation and glucose homeostasis.

Kisspeptin receptor in GtoPdb v.2023.1

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