Prostanoid receptors (version 2019.5) in the IUPHAR/BPS Guide to Pharmacology Database

Richard M. Breyer (Author)

Vanderbilt University

Lucie Clapp (Author)

University College London https://orcid.org/0000-0001-7802-4481

Robert A. Coleman (Author)

Pharmagene Laboratories

Mark Giembycz (Author)

University of Calgary

Akos Heinemann (Author)

Otto Loewi Research Center (for Vascular Biology, Immunology and Inflammation) https://orcid.org/0000-0002-8554-2372

Rebecca Hills (Author)

University of Edinburgh

Robert L. Jones (Author)

University of Strathclyde

Shuh Narumiya (Author)

Kyoto University Faculty of Medicine

Xavier Norel (Author)

Laboratory for Vascular Translational Science https://orcid.org/0000-0003-0734-3359

Roy Pettipher (Author)

Atopix Therapeutics Ltd

Yukihiko Sugimoto (Author)

Kumamoto University

Mohib Uddin (Author)

AstraZeneca https://orcid.org/0000-0002-2412-2657

David F. Woodward (Author)

Allergan plc

Chengcan Yao (Author)

University of Edinburgh https://orcid.org/0000-0003-3754-2842

Period(s):
GtoPdb_general: generated Wed Nov 13 10:11:49 2019; family F58, Prostanoid receptors; version 2019.5., GtoPdb_hierarchy: ( F58 O338 O339 O340 O341 O342 O343 O344 O345 O346 I58 ), GtoPdb_authors: 305 312 314 315 317 318 542 543 828 830 831 1045 1046 1074, GtoPdb_references: 6166 6167 6168 6169 6170 6171 6172 6173 6174 6175 6176 6177 6178 6179 6180 6181 6182 6183 6184 6185 6186 6187 6188 6189 6190 6191 6192 6193 6194 6195 6196 6197 6198 6199 6200 6201 6202 6203 6204 6205 6206 6207 6208 6209 6210 6211 6212 6213 6214 6215 6216 6217 6218 6219 6220 6221 6222 6223 6224 6225 6226 6227 6228 6229 6230 6231 6232 6233 6234 6235 6236 6237 6238 6239 6240 6241 6242 6243 6244 6245 6246 6247 6248 6249 6250 6251 6252 6253 6254 6255 6256 6257 6258 6259 6260 6261 6262 6263 6264 6265 6266 6267 6268 6269 6270 6271 6272 6273 6274 6275 6276 6277 6278 6279 6280 6281 6282 6283 6284 6285 6286 6287 6288 6289 6291 6292 6293 6294 6295 6296 6297 6298 6299 6300 6301 6302 6303 6304 6305 6306 6307 6308 6309 6310 6311 6312 6313 6314 6315 6316 6317 6318 6319 6320 6321 6322 6323 6324 6325 6326 6327 6328 6329 6330 6331 6332 6333 6334 6335 6336 6337 6338 6339 6340 6341 6342 6343 6344 6345 6346 6347 6348 6349 6350 6351 6352 6353 6354 6355 6356 6357 6358 6359 6360 6361 6362 6363 6364 6365 6366 6367 6368 6369 6370 6372 6373 6374 6375 6376 6377 6378 6379 6380 6381 6382 6383 6384 6385 6386 6387 6388 6389 6390 6391 6392 6393 6395 6396 6399 6400 6401 6402 6403 6404 6405 6406 6407 6408 6409 6410 6411 6412 6413 6414 6415 6416 6417 6418 6419 6420 6421 6422 6423 6424 6425 6426 6427 6428 6429 6430 6431 6432 6433 6434 6435 6436 6437 6438 6439 6440 6441 6442 6443 6444 6445 6446 6447 6448 6449 6450 6451 6452 6453 6454 6455 6456 6457 6458 6459 6460 6461 6462 6463 6464 6465 6466 6467 6468 6469 6470 6471 6472 6473 6474 6475 6476 6477 6478 6479 6480 6481 6482 6483 6484 6485 6486 6487 6488 6489 6490 6491 6492 6493 6494 6495 6496 6497 6498 6499 6500 6501 6502 6503 6504 6505 6506 6507 6508 6509 6510 6511 6512 6513 6514 6515 6516 6517 6518 6519 6520 6525 6526 6530 6531 6532 6533 6534 6535 6539 6540 6541 6542 6543 6544 6545 6546 6547 6548 6549 6550 6551 13905 13930 13931 13933 13934 13938 13939 13944 14369 14371 14372 14373 14579 14653 14654 15111 15113 15244 15245 15251 15252 15253 18577 18578 18580 19335 19336 19337 19338 19339 19340 19341 19342 19343 19344 19345 19346 19347 19348 19349 19350 19351 19353 19354 19355 19356 19357 19358 19359 19360 19361 19364 19365 19366 19367 19368 19369 19370 19371 19372 19373 19374 19375 19376 19377 19379 19380 19381 19382 19383 19384 19386 19387 19388 19389 19390 19391 19392 19393 19394 19395 19396 19397 19398 19399 19400 19401 19402 19403 19404 19405 19406 19407 19408 19409 19410 19411 19412 19413 19414 19415 19416 19417 19418 19419 19420 19421 19422 19423 19424 19425 19426 19427 19428 19461 19462 19463 19464 19465 19466 19467 19468 19469 19470 19471 19472 19473 19474 19475 19476 19477 19478 19479 19480 19481 19482 19483 19484 19485 19486 19487 19488 19489 19490 19491 19492 19493 19494 19500 19501 19503 19504 19505 19506 19507 19508 19509 19510 19511 19512 19513 19514 19515 19516 19517 19518 19519 19520 19521 19522 19523 19524 19525 19526 19527 19528 19529 19530 19531 19532 19533 19534 19535 19536 19537 19538 19539 19540 19541 19542 19543 19544 19545 19546 19547 19548 19549 19550 19551 19552 20070 20071 20072 20073 20074 20075 20076 20077 20078 20079 20080 20081 20082 20083 20305 20306 20350 20351 20352 20353 20354 20355 20356 20357 20358 20359 20360 20361 20362 20363 20364 20365 20367 20368 20369 20370 20371 20372 20373 20374 20375 20376 20377 20378 20379 20380 20381 20382 20383 20384 20385 20386 20387 20388 20389 20390 23120 24510 24722 25297 27465 28485 28486 28487 28492 28510 29831 30450 30565 31421 31448 31449 31451 31452 31453 31454 31455 31456 31457 31458 31459 31460 31461 31462 31463 31464 31465 31466 31570 31571 31572 31573 31574 31575 31903 32247 32248 32260 32261 32504 33399 33400 33401 33402 33403 33404 33405 33406 33422 33427 34012 34489 34774 36286 36289 36627 36629 36654 36655 36657 36658 36659 36660 36661 36662 37377 37378 38413 38414

Abstract


Prostanoid receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Prostanoid Receptors [659]) are activated by the endogenous ligands prostaglandins PGD2, PGE1, PGE2 , PGF, PGH2, prostacyclin [PGI2] and thromboxane A2. Measurement of the potency of PGI2 and thromboxane A2 is hampered by their instability in physiological salt solution; they are often replaced by cicaprost and U46619, respectively, in receptor characterization studies.

Published
13-Nov-2019
How to Cite
Breyer, R. M. (2019) “Prostanoid receptors (version 2019.5) in the IUPHAR/BPS Guide to Pharmacology Database”, IUPHAR/BPS Guide to Pharmacology CITE, 2019(5). doi: 10.2218/gtopdb/F58/2019.5.
Section
Summaries