Voltage-gated potassium channels (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database
DOI:
https://doi.org/10.2218/gtopdb/F81/2019.4Abstract
The 6TM family of K channels comprises the voltage-gated KV subfamilies, the EAG subfamily (which includes hERG channels), the Ca2+-activated Slo subfamily (actually with 7TM, termed BK) and the Ca2+-activated SK subfamily. These channels possess a pore-forming α subunit that comprise tetramers of identical subunits (homomeric) or of different subunits (heteromeric). Heteromeric channels can only be formed within subfamilies (e.g. Kv1.1 with Kv1.2; Kv7.2 with Kv7.3). The pharmacology largely reflects the subunit composition of the functional channel.Downloads
Published
16-Sep-2019
How to Cite
Attali, B. (2019) “Voltage-gated potassium channels (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database”, IUPHAR/BPS Guide to Pharmacology CITE, 2019(4). doi: 10.2218/gtopdb/F81/2019.4.
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