Vasopressin and oxytocin receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

Authors

  • Daniel Bichet University of North Carolina
  • Michel Bouvier Université de Montréal https://orcid.org/0000-0003-1128-0100
  • Bice Chini CNR Institute of Neuroscience
  • Gerald Gimpl Johannes Gutenberg-Universität
  • Gilles Guillon Institut de Génomique Fonctionnelle
  • Tadashi Kimura Osaka University
  • Mark Knepper National Institutes of Health
  • Stephen Lolait University of Bristol https://orcid.org/0000-0001-7228-8072
  • Maurice Manning University of Toledo College of Medicine
  • Bernard Mouillac Université de Montpellier https://orcid.org/0000-0002-3906-8673
  • Anne-Marie O'Carroll University of Bristol https://orcid.org/0000-0001-5255-8506
  • Claudine Serradeil-Le Gal Sanofi Synthelabo Recherche
  • Melvyn Soloff University of Texas
  • Joseph G. Verbalis Georgetown University Medical Center
  • Mark Wheatley University of Birmingham
  • Hans H. Zingg McGill University

DOI:

https://doi.org/10.2218/gtopdb/F66/2019.4

Abstract

Vasopressin (AVP) and oxytocin (OT) receptors (nomenclature as recommended by NC-IUPHAR [92]) are activated by the endogenous cyclic nonapeptides vasopressin and oxytocin. These peptides are derived from precursors which also produce neurophysins (neurophysin I for oxytocin; neurophysin II for vasopressin). Vasopressin and oxytocin differ at only 2 amino acids (positions 3 and 8). There are metabolites of these neuropeptides that may be biologically active [67].

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Published

16-Sep-2019

Issue

Vol. 2019 No. 4 (2019)

Section

Summaries

How to Cite

“Vasopressin and oxytocin receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database” (2019) IUPHAR/BPS Guide to Pharmacology CITE, 2019(4). doi:10.2218/gtopdb/F66/2019.4.