IUPHAR/BPS Guide to Pharmacology CITE
https://doi.org/10.2218/gtopdb/F141/2021.3

SLC3 and SLC7 families of heteromeric amino acid transporters (HATs) in GtoPdb v.2021.3



Yoshikatsu Kanai1
  1. Osaka University, Japan


Abstract

The SLC3 and SLC7 families combine to generate functional transporters, where the subunit composition is a disulphide-linked combination of a heavy chain (SLC3 family) with a light chain (SLC7 family) [1].

Contents

This is a citation summary for SLC3 and SLC7 families of heteromeric amino acid transporters (HATs) in the Guide to Pharmacology database (GtoPdb). It exists purely as an adjunct to the database to facilitate the recognition of citations to and from the database by citation analyzers. Readers will almost certainly want to visit the relevant sections of the database which are given here under database links.

GtoPdb is an expert-driven guide to pharmacological targets and the substances that act on them. GtoPdb is a reference work which is most usefully represented as an on-line database. As in any publication this work should be appropriately cited, and the papers it cites should also be recognized. This document provides a citation for the relevant parts of the database, and also provides a reference list for the research cited by those parts. For further details see [2].

Please note that the database version for the citations given in GtoPdb are to the most recent preceding version in which the family or its subfamilies and targets were substantially changed. The links below are to the current version. If you need to consult the cited version, rather than the most recent version, please contact the GtoPdb curators.

Database links

SLC3 and SLC7 families of heteromeric amino acid transporters (HATs)
https://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=141
    SLC3 family
    https://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=168
        Transporters
                rBAT
                https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=889
                4F2hc
                https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=890
    SLC7 family
    https://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=169
        Transporters
                CAT1(High affinity cationic amino acid transporter 1)
                https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=891
                CAT2(Low affinity cationic amino acid transporter 2)
                https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=892
                CAT3(Cationic amino acid transporter 3)
                https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=893
                CAT4(Cationic amino acid transporter 4)
                https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=894
                Probable cationic amino acid transporter
                https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=895
                LAT1(L-type amino acid transporter 1)
                https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=896
                LAT2(L-type amino acid transporter 2)
                https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=897
                y+LAT1(y+L amino acid transporter 1)
                https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=898
                y+LAT2(y+L amino acid transporter 2)
                https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=899
                b0,+AT(b0,+-type amino acid transporter 1)
                https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=900
                Asc-1(Asc-type amino acid transporter 1)
                https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=901
                xCT(Cystine/glutamate transporter)
                https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=902
                AGT1
                https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=903

References

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