IUPHAR/BPS Guide to Pharmacology CITE
https://doi.org/10.2218/gtopdb/F74/2019.4
Inwardly rectifying potassium channels (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database
John P. Adelman1,
David E. Clapham2,
Hiroshi Hibino3,
Atsushi Inanobe3,
Lily Y. Jan4,
Andreas Karschin5,
Yoshihiro Kubo6,
Yoshihisa Kurachi3,
Michel Lazdunski7,
Takashi Miki8,
Colin G. Nichols9,
Lawrence G. Palmer10,
Wade L. Pearson9,
Henry Sackin11,
Susumu Seino8,
Paul A. Slesinger12,
Stephen Tucker13 and
Carol A. Vandenberg14
- Oregon Health & Science University, USA
- Harvard Medical School, USA
- Osaka University, Japan
- University of California San Francisco, USA
- University of Würzburg, Germany
- National Institute for Physiological Sciences, Japan
- CNRS Valbonne, France
- Kobe University, Japan
- Washington University, USA
- Weill-Cornell Medical College, USA
- Rosalind Franklin University, USA
- Icahn School of Medicine at Mount Sinai, USA
- University of Oxford, UK
- University of California Santa Barbara, USA
Abstract
The 2TM domain family of K channels are also known as the inward-rectifier K channel family. This family includes the strong inward-rectifier K channels (Kir2.x) that are constitutively active, the G-protein-activated inward-rectifier K channels (Kir3.x) and the ATP-sensitive K channels (Kir6.x, which combine with sulphonylurea receptors (SUR1-3)). The pore-forming α subunits form tetramers, and heteromeric channels may be formed within subfamilies (e.g. Kir3.2 with Kir3.3).
Contents
This is a citation summary for Inwardly rectifying potassium channels in the
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Please note that the database version for the citations given in
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Database links
Inwardly rectifying potassium channels
http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=74
Introduction to Inwardly rectifying potassium channels
http://www.guidetopharmacology.org/GRAC/FamilyIntroductionForward?familyId=74
Channels and Subunits
Kir1.1
http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=429
Kir2.1
http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=430
Kir2.2
http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=431
Kir2.3
http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=432
Kir2.4
http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=433
Kir3.1
http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=434
Kir3.2
http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=435
Kir3.3
http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=436
Kir3.4
http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=437
Kir4.1
http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=438
Kir4.2
http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=439
Kir5.1
http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=440
Kir6.1
http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=441
Kir6.2
http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=442
Kir7.1
http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=443
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