IUPHAR/BPS Guide to Pharmacology CITE
https://doi.org/10.2218/gtopdb/F53/2019.4
Parathyroid hormone receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database
Alessandro Bisello1,
Michael Chorev2,
Peter A. Friedman1,
Tom Gardella3,
Rebecca Hills4,
Harald Jueppner3,
T. John Martin5,
Robert A. Nissenson6,
John Thomas Potts, Jr.3,
Caroline Silve7,
Ted B. Usdin8 and
Jean-Pierre Vilardaga1
- University of Pittsburgh, USA
- Harvard Medical School, USA
- Massachusetts General Hospital, USA
- University of Edinburgh, UK
- University of Melbourne, Australia
- University of California San Francisco, USA
- INSERM, France
- National Institute of Mental Health, USA
Abstract
The parathyroid hormone receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Parathyroid Hormone Receptors [47]) are family B G protein-coupled receptors. The parathyroid hormone (PTH)/parathyroid hormone-related peptide (PTHrP) receptor (PTH1 receptor) is activated by precursor-derived peptides: PTH (84 amino acids), and PTHrP (141 amino-acids) and related peptides (PTH-(1-34), PTHrP-(1-36)). The parathyroid hormone 2 receptor (PTH2 receptor) is activated by the precursor-derived peptide TIP39 (39 amino acids). [125I]PTH may be used to label both PTH1 and PTH2 receptors.
Contents
This is a citation summary for Parathyroid hormone receptors in the
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Database links
Parathyroid hormone receptors
http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=53
Introduction to Parathyroid hormone receptors
http://www.guidetopharmacology.org/GRAC/FamilyIntroductionForward?familyId=53
Receptors
PTH1 receptor
http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=331
PTH2 receptor
http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=332
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