TY - JOUR AU - Daniel Bichet AU - Michel Bouvier AU - Bice Chini AU - Gerald Gimpl AU - Gilles Guillon AU - Tadashi Kimura AU - Mark Knepper AU - Stephen Lolait AU - Maurice Manning AU - Bernard Mouillac AU - Anne-Marie O'Carroll AU - Claudine Serradeil-Le Gal AU - Melvyn Soloff AU - Joseph G. Verbalis AU - Mark Wheatley AU - Hans H. Zingg PY - 2019/09/16 Y2 - 2024/03/28 TI - Vasopressin and oxytocin receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database JF - IUPHAR/BPS Guide to Pharmacology CITE JA - GtoPdb CITE VL - 2019 IS - 4 SE - Summaries DO - 10.2218/gtopdb/F66/2019.4 UR - http://journals.ed.ac.uk/gtopdb-cite/article/view/3218 AB - Vasopressin (AVP) and oxytocin (OT) receptors (nomenclature as recommended by NC-IUPHAR [92]) are activated by the endogenous cyclic nonapeptides vasopressin and oxytocin. These peptides are derived from precursors which also produce neurophysins (neurophysin I for oxytocin; neurophysin II for vasopressin). Vasopressin and oxytocin differ at only 2 amino acids (positions 3 and 8). There are metabolites of these neuropeptides that may be biologically active [67]. ER -