TY - JOUR AU - Rebecca Hills AU - Satoshi Ishii AU - Sonia Jancar AU - Thomas McIntyre AU - Ewa Ninio AU - Chris O'Neill AU - Francisco Jose Oliveira Rios AU - Jeffery B. Travers AU - Mark Whittaker PY - 2019/09/16 Y2 - 2024/03/29 TI - Platelet-activating factor receptor (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database JF - IUPHAR/BPS Guide to Pharmacology CITE JA - GtoPdb CITE VL - 2019 IS - 4 SE - Summaries DO - 10.2218/gtopdb/F55/2019.4 UR - http://journals.ed.ac.uk/gtopdb-cite/article/view/3207 AB - Platelet-activating factor (PAF, 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) is an ether phospholipid mediator associated with platelet coagulation, but also subserves inflammatory roles. The PAF receptor (provisional nomenclature recommended by NC-IUPHAR [37]) is activated by PAF and other suggested endogenous ligands are oxidized phosphatidylcholine [73] and lysophosphatidylcholine [96]. It may also be activated by bacterial lipopolysaccharide [89]. ER -