TY - JOUR AU - Alessandro Bisello AU - Michael Chorev AU - Peter A. Friedman AU - Tom Gardella AU - Rebecca Hills AU - Harald Jueppner AU - T. John Martin AU - Robert A. Nissenson AU - John Thomas Potts, Jr. AU - Caroline Silve AU - Ted B. Usdin AU - Jean-Pierre Vilardaga PY - 2019/09/16 Y2 - 2024/03/28 TI - Parathyroid hormone receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database JF - IUPHAR/BPS Guide to Pharmacology CITE JA - GtoPdb CITE VL - 2019 IS - 4 SE - Summaries DO - 10.2218/gtopdb/F53/2019.4 UR - http://journals.ed.ac.uk/gtopdb-cite/article/view/3205 AB - The parathyroid hormone receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Parathyroid Hormone Receptors [47]) are family B G protein-coupled receptors. The parathyroid hormone (PTH)/parathyroid hormone-related peptide (PTHrP) receptor (PTH1 receptor) is activated by precursor-derived peptides: PTH (84 amino acids), and PTHrP (141 amino-acids) and related peptides (PTH-(1-34), PTHrP-(1-36)). The parathyroid hormone 2 receptor (PTH2 receptor) is activated by the precursor-derived peptide TIP39 (39 amino acids). [125I]PTH may be used to label both PTH1 and PTH2 receptors. ER -