Kisspeptin receptor in GtoPdb v.2023.1

Anthony P. Davenport; Janet J. Maguire; Edward J. Mead; Adam J Pawson

doi:10.2218/gtopdb/F34/2023.1

Kisspeptin receptor in GtoPdb v.2023.1

Anthony P. Davenport University of Cambridge https://orcid.org/0000-0002-2096-3117
Janet J. Maguire University of Cambridge https://orcid.org/0000-0002-9254-7040
Edward J. Mead University of Cambridge
Adam J Pawson The University of Edinburgh https://orcid.org/0000-0003-2280-845X

Abstract

The kisspeptin receptor (nomenclature as agreed by the NC-IUPHAR Subcommittee on the kisspeptin receptor [11]), like neuropeptide FF (NPFF), prolactin-releasing peptide (PrP) and QRFP receptors (provisional nomenclature) responds to endogenous peptides with an arginine-phenylalanine-amide (RFamide) motif. kisspeptin-54 (KP54, originally named metastin), kisspeptin-13 (KP13) and kisspeptin-10 (KP10) are biologically-active peptides cleaved from the KISS1 (Q15726) gene product. Kisspeptins have roles in, for example, cancer metastasis, fertility/puberty regulation and glucose homeostasis.

DOI: https://doi.org/10.2218/gtopdb/F34/2023.1

Published

26-Apr-2023

How to Cite

Davenport, A. P., Maguire, J. J., Mead, E. J. and Pawson, A. J. (2023) “Kisspeptin receptor in GtoPdb v.2023.1”, IUPHAR/BPS Guide to Pharmacology CITE, 2023(1). doi: 10.2218/gtopdb/F34/2023.1.

Download Citation

Issue

Vol 2023 No 1 (2023)

Section

Summaries

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.