SLC66 Lysosomal amino acid transporters in GtoPdb v.2021.2

Abstract


This is a family of 5 evolutionarily related proteins. Their structural similarities suggest that they are transporters. Biochemical evidence supports transporter activity for SLC66A1 (LAAT1) and SLC66A4 (CTNS; Cystinosin). The functions of the 3 remaining members of the family are undetermined.

Published
25-Jun-2021
How to Cite
Gyimesi, G. and Hediger, M. A. (2021) “SLC66 Lysosomal amino acid transporters in GtoPdb v.2021.2”, IUPHAR/BPS Guide to Pharmacology CITE, 2021(2). doi: 10.2218/gtopdb/F1048/2021.2.
Section
Summaries