Kisspeptin receptor (version 2020.4) in the IUPHAR/BPS Guide to Pharmacology Database

Anthony P. Davenport; Janet J. Maguire; Edward J. Mead; Adam J. Pawson

doi:10.2218/gtopdb/F34/2020.4

Kisspeptin receptor (version 2020.4) in the IUPHAR/BPS Guide to Pharmacology Database

Anthony P. Davenport University of Cambridge https://orcid.org/0000-0002-2096-3117
Janet J. Maguire University of Cambridge https://orcid.org/0000-0002-9254-7040
Edward J. Mead University of Cambridge
Adam J. Pawson The University of Edinburgh https://orcid.org/0000-0003-2280-845X

Abstract

The kisspeptin receptor (nomenclature as agreed by the NC-IUPHAR Subcommittee on the kisspeptin receptor [9]), like neuropeptide FF (NPFF), prolactin-releasing peptide (PrP) and QRFP receptors (provisional nomenclature) responds to endogenous peptides with an arginine-phenylalanine-amide (RFamide) motif. kisspeptin-54 (KP54, originally named metastin), kisspeptin-13 (KP13) and kisspeptin-10 (KP10) are biologically-active peptides cleaved from the KISS1 (Q15726) gene product. Kisspeptins have roles in, for example, cancer metastasis, fertility/puberty regulation and glucose homeostasis.

DOI: https://doi.org/10.2218/gtopdb/F34/2020.4

Published

24-Sep-2020

How to Cite

Davenport, A. P., Maguire, J. J., Mead, E. J. and Pawson, A. J. (2020) “Kisspeptin receptor (version 2020.4) in the IUPHAR/BPS Guide to Pharmacology Database”, IUPHAR/BPS Guide to Pharmacology CITE, 2020(4). doi: 10.2218/gtopdb/F34/2020.4.

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Issue

Vol 2020 No 4 (2020)

Section

Summaries

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