Somatostatin receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database
Abstract
Somatostatin (somatotropin release inhibiting factor) is an abundant neuropeptide, which acts on five subtypes of somatostatin receptor (SST1-SST5; nomenclature as agreed by the NC-IUPHAR Subcommittee on Somatostatin Receptors [89]). Activation of these receptors produces a wide range of physiological effects throughout the body including the inhibition of secretion of many hormones. Endogenous ligands for these receptors are somatostatin-14 (SRIF-14) and somatostatin-28 (SRIF-28). cortistatin-14 has also been suggested to be an endogenous ligand for somatostatin receptors [56].
Published
16-Sep-2019
How to Cite
Bosquet, C., Castaño, J. P., Csaba, Z., Culler, M., Dournaud, P., Epelbaum, J., Feniuk, W., Harmar, A., Hills, R., Hofland, L., Hoyer, D., Humphrey, P. P. A., Kreienkamp, H.-J., Lupp, A., Melmed, S., Meyerhof, W., O’Carroll, A.-M., Patel, Y. C., Reisine, T., Reubi, J.-C., Schindler, M., Schmid, H., Schonbrunn, A., Schulz, S., Taylor, J. E., Tulipano, G., Vezzani, A. and Wester, H.-J. (2019) “Somatostatin receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database”, IUPHAR/BPS Guide to Pharmacology CITE, 2019(4). doi: 10.2218/gtopdb/F61/2019.4.
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