Platelet-activating factor receptor (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database
Abstract
Platelet-activating factor (PAF, 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) is an ether phospholipid mediator associated with platelet coagulation, but also subserves inflammatory roles. The PAF receptor (provisional nomenclature recommended by NC-IUPHAR [37]) is activated by PAF and other suggested endogenous ligands are oxidized phosphatidylcholine [73] and lysophosphatidylcholine [96]. It may also be activated by bacterial lipopolysaccharide [89].
Published
16-Sep-2019
How to Cite
Hills, R., Ishii, S., Jancar, S., McIntyre, T., Ninio, E., O’Neill, C., Oliveira Rios, F. J., Travers, J. B. and Whittaker, M. (2019) “Platelet-activating factor receptor (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database”, IUPHAR/BPS Guide to Pharmacology CITE, 2019(4). doi: 10.2218/gtopdb/F55/2019.4.
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