Kisspeptin receptor (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

Anthony P. Davenport; Janet J. Maguire; Edward J. Mead

doi:10.2218/gtopdb/F34/2019.4

Kisspeptin receptor (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

Anthony P. Davenport University of Cambridge https://orcid.org/0000-0002-2096-3117
Janet J. Maguire University of Cambridge https://orcid.org/0000-0002-9254-7040
Edward J. Mead University of Cambridge

Abstract

The kisspeptin receptor (nomenclature as agreed by the NC-IUPHAR Subcommittee on the kisspeptin receptor [9]), like neuropeptide FF (NPFF), prolactin-releasing peptide (PrP) and QRFP receptors (provisional nomenclature) responds to endogenous peptides with an arginine-phenylalanine-amide (RFamide) motif. kisspeptin-54 (KP54, originally named metastin), kisspeptin-13 (KP13) and kisspeptin-10 (KP10) are biologically-active peptides cleaved from the KISS1 (Q15726) gene product. Kisspeptins have roles in, for example, cancer metastasis, fertility/puberty regulation and glucose homeostasis.

DOI: https://doi.org/10.2218/gtopdb/F34/2019.4

Published

16-Sep-2019

How to Cite

Davenport, A. P., Maguire, J. J. and Mead, E. J. (2019) “Kisspeptin receptor (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database”, IUPHAR/BPS Guide to Pharmacology CITE, 2019(4). doi: 10.2218/gtopdb/F34/2019.4.

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Issue

Vol 2019 No 4 (2019)

Section

Summaries

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