Angiotensin receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database
Abstract
The actions of angiotensin II (Ang II) are mediated by AT1 and AT2 receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Angiotensin receptors [61, 152]), which have around 30% sequence similarity. The decapeptide angiotensin I, the octapeptide angiotensin II and the heptapeptide angiotensin III are endogenous ligands. losartan, candesartan, telmisartan, etc. are clinically used AT1 receptor blockers.
Published
16-Sep-2019
How to Cite
Alexander, W., Bernstein, K. E., Catt, K. J., de Gasparo, M., Dhanachandra Singh, K., Eguchi, S., Escher, E., Goodfriend, T. L., Horiuchi, M., Hunyady, L., Husain, A., Inagami, T., Karnik, S., Kemp, J., Thomas, W. G., Timmermans, P. B. M. W. M., Tirupula, K., Unal, H., Unger, T. and Vanderheyden, P. (2019) “Angiotensin receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database”, IUPHAR/BPS Guide to Pharmacology CITE, 2019(4). doi: 10.2218/gtopdb/F6/2019.4.
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