IUPHAR/BPS Guide to Pharmacology CITE
https://doi.org/10.2218/gtopdb/F147/2023.1
SLC25 family of mitochondrial transporters in GtoPdb v.2023.1
Edmund R.S. Kunji1
- University of Cambridge, UK
Abstract
Mitochondrial carriers are nuclear-encoded proteins, which translocate solutes across the inner mitochondrial membrane. Mitochondrial carriers are functional as monomers and have six TM alpha-helices and the termini in the mitochondrial intermembrane space.
Contents
This is a citation summary for SLC25 family of mitochondrial transporters in the
Guide to Pharmacology
database (GtoPdb). It exists purely as an adjunct to the database to
facilitate the recognition of citations to and from the database by
citation analyzers. Readers will almost certainly want to visit the
relevant sections of the database which are given here under database
links.
GtoPdb is an expert-driven
guide to pharmacological targets and the substances that act on them.
GtoPdb is a reference work which is most usefully represented as an
on-line database. As in any publication this work should be
appropriately cited, and the papers it cites should also be
recognized. This document provides a citation for the relevant parts
of the database, and also provides a reference list for the research
cited by those parts. For further details see [1].
Please note that the database version for the citations given in
GtoPdb are to the most recent preceding version
in which the family or its subfamilies and targets were substantially
changed. The links below are to the current version. If you
need to consult the cited version, rather than the most recent version, please contact
the GtoPdb curators.
Database links
SLC25 family of mitochondrial transporters
https://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=147
Mitochondrial di- and tri-carboxylic acid transporter subfamily
https://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=203
Transporters
CIC(Mitochondrial citrate transporter)
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1051
DIC(Mitochondrial dicarboxylate transporter)
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1052
OGC(Mitochondrial oxoglutarate carrier)
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1053
ODC(Mitochondrial oxodicarboxylate carrier)
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1057
SLC25A34
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1085
SLC25A35
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1086
Mitochondrial amino acid transporter subfamily
https://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=204
Transporters
solute carrier family 25 member 47
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2558
solute carrier family 25 member 48
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2559
AGC1
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1054
AGC2
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1055
GC2(Mitochondrial glutamate carrier 2)
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1056
GC1(Mitochondrial glutamate carrier 1)
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1058
ORC2(Mitochondrial ornithine transporter 2)
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1059
ORC1(Mitochondrial ornithine transporter 1 )
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1060
CAC(Carnitine/acylcarnitine carrier)
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1076
ORNT3
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1081
SLC25A38
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1089
CGI-69
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1090
MCFP
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1091
SLC25A44
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1094
SLC25A45
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1095
Mitochondrial phosphate transporters
https://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=205
Transporters
PHC(Mitochondrial phosphate carrier)
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1061
Mitochondrial nucleotide transporter subfamily
https://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=206
Transporters
ANT1(Mitochondrial adenine nucleotide translocator 1)
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1062
ANT2(Mitochondrial adenine nucleotide translocator 2)
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1063
ANT3(Mitochondrial adenine nucleotide translocator 3)
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1064
ANT4(Mitochondrial adenine nucleotide translocator 4)
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1065
GDC(Graves disease carrier)
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1071
PMP34(Peroxisomal membrane protein)
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1072
DNC(Deoxynucleotide carrier 1)
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1073
SAMC1(S-Adenosylmethionine carrier)
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1074
SLC25A42
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1075
APC1(Mitochondrial phosphate carrier 1)
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1077
APC2(Mitochondrial phosphate carrier 2)
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1078
APC3(Mitochondrial phosphate carrier 3)
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1079
MFTC(MFT)
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1083
PNC1
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1084
PNC2(SLC25A36)
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1087
SCaMC-3L
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1092
SLC25A43
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1093
Mitochondrial uncoupling proteins
https://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=207
Transporters
UCP1(Uncoupling protein 1)
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1066
UCP2(Uncoupling protein 2)
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1067
UCP3(Uncoupling protein 3)
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1068
UCP4(Uncoupling protein 4)
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1069
UCP5(Uncoupling protein 5)
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1070
KMCP1
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1082
Miscellaneous SLC25 mitochondrial transporters
https://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=209
Transporters
mitochondrial carrier 1
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2554
mitochondrial carrier 2
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2555
solute carrier family 25 member 51
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2560
solute carrier family 25 member 52
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2561
solute carrier family 25 member 53
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2562
Mitoferrin2
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1080
Mitoferrin1
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1088
SLC25A46
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1096
References
- Buneman P, Christie G, Davies JA, Dimitrellou R, Harding SD, Pawson AJ, Sharman JL and Wu Y. (2020) Why data citation isn't working, and what to do about it Database 2020 [PMID:32367113]
- Fiermonte G, Dolce V, David L, Santorelli FM, Dionisi-Vici C, Palmieri F and Walker JE. (2003) The mitochondrial ornithine transporter. Bacterial expression, reconstitution, functional characterization, and tissue distribution of two human isoforms. J Biol Chem 278: 32778-83 [PMID:12807890]
- Fiermonte G, Paradies E, Todisco S, Marobbio CM and Palmieri F. (2009) A novel member of solute carrier family 25 (SLC25A42) is a transporter of coenzyme A and adenosine 3',5'-diphosphate in human mitochondria. J Biol Chem 284: 18152-9 [PMID:19429682]