IUPHAR/BPS Guide to Pharmacology CITE
https://doi.org/10.2218/gtopdb/F66/2023.1

Vasopressin and oxytocin receptors in GtoPdb v.2023.1



Daniel Bichet1, Michel Bouvier2, Bice Chini3, Gerald Gimpl4, Gilles Guillon5, Tadashi Kimura6, Mark Knepper7, Stephen Lolait8, Maurice Manning9, Bernard Mouillac10, Anne-Marie O'Carroll8, Claudine Serradeil-Le Gal11, Melvyn Soloff12, Joseph G. Verbalis13, Mark Wheatley14 and Hans H. Zingg15
  1. University of North Carolina, USA
  2. Université de Montréal, Canada
  3. CNR Institute of Neuroscience, Italy
  4. Johannes Gutenberg-Universität, Germany
  5. Institut de Génomique Fonctionnelle, France
  6. Osaka University, Japan
  7. National Institutes of Health, USA
  8. University of Bristol, UK
  9. University of Toledo College of Medicine, USA
  10. Université de Montpellier, France
  11. VibeoSphen, France
  12. University of Texas, USA
  13. Georgetown University Medical Center, USA
  14. University of Birmingham, UK
  15. McGill University, Canada


Abstract

Vasopressin (AVP) and oxytocin (OT) receptors (nomenclature as recommended by NC-IUPHAR [94]) are activated by the endogenous cyclic nonapeptides vasopressin and oxytocin. These peptides are derived from precursors which also produce neurophysins (neurophysin I for oxytocin; neurophysin II for vasopressin). Vasopressin and oxytocin differ at only 2 amino acids (positions 3 and 8). There are metabolites of these neuropeptides that may be biologically active [69].

Contents

This is a citation summary for Vasopressin and oxytocin receptors in the Guide to Pharmacology database (GtoPdb). It exists purely as an adjunct to the database to facilitate the recognition of citations to and from the database by citation analyzers. Readers will almost certainly want to visit the relevant sections of the database which are given here under database links.

GtoPdb is an expert-driven guide to pharmacological targets and the substances that act on them. GtoPdb is a reference work which is most usefully represented as an on-line database. As in any publication this work should be appropriately cited, and the papers it cites should also be recognized. This document provides a citation for the relevant parts of the database, and also provides a reference list for the research cited by those parts. For further details see [40].

Please note that the database version for the citations given in GtoPdb are to the most recent preceding version in which the family or its subfamilies and targets were substantially changed. The links below are to the current version. If you need to consult the cited version, rather than the most recent version, please contact the GtoPdb curators.

Database links

Vasopressin and oxytocin receptors
https://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=66
Introduction to Vasopressin and oxytocin receptors
https://www.guidetopharmacology.org/GRAC/FamilyIntroductionForward?familyId=66
    Receptors
            V1A receptor
            https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=366
            V1B receptor
            https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=367
            V2 receptor
            https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=368
            OT receptor
            https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=369

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