IUPHAR/BPS Guide to Pharmacology CITE
https://doi.org/10.2218/gtopdb/F446/2021.3

Succinate receptor in GtoPdb v.2021.3



Anthony P. Davenport1, Julien Hanson2 and Wen Chiy Liew3
  1. University of Cambridge, UK
  2. University of Liege, Belgium
  3. University of Edinburgh, UK


Abstract

Nomenclature as recommended by NC-IUPHAR [8]. The Succinate receptor was identified as being activated by physiological levels of the Kreb's cycle intermediate succinate and other dicarboxylic acids such as maleate in 2004. Since its pairing with its endogenous ligand, the receptor has been the focus of intensive research and its role has been evidenced in various (patho)physiological processes such as regulation of renin production, retinal angiogenesis, inflammation or the immune response.

Contents

This is a citation summary for Succinate receptor in the Guide to Pharmacology database (GtoPdb). It exists purely as an adjunct to the database to facilitate the recognition of citations to and from the database by citation analyzers. Readers will almost certainly want to visit the relevant sections of the database which are given here under database links.

GtoPdb is an expert-driven guide to pharmacological targets and the substances that act on them. GtoPdb is a reference work which is most usefully represented as an on-line database. As in any publication this work should be appropriately cited, and the papers it cites should also be recognized. This document provides a citation for the relevant parts of the database, and also provides a reference list for the research cited by those parts. For further details see [5].

Please note that the database version for the citations given in GtoPdb are to the most recent preceding version in which the family or its subfamilies and targets were substantially changed. The links below are to the current version. If you need to consult the cited version, rather than the most recent version, please contact the GtoPdb curators.

Database links

Succinate receptor
https://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=446
Introduction to Succinate receptor
https://www.guidetopharmacology.org/GRAC/FamilyIntroductionForward?familyId=446
    Receptors
            succinate receptor
            https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=166

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