IUPHAR/BPS Guide to Pharmacology CITE
https://doi.org/10.2218/gtopdb/F1022/2019.4

Receptor guanylyl cyclase (RGC) family (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database



Annie Beuve1, Peter Brouckaert2, John C. Burnett, Jr.3, Andreas Friebe4, John Garthwaite5, Adrian J. Hobbs6, Doris Koesling7, Michaela Kuhn8, Lincoln R. Potter9, Michael Russwurm10, Harald H.H.W. Schmidt11, Johannes-Peter Stasch12 and Scott A. Waldman13
  1. Rutgers University, USA
  2. Vlaams Instituut voor Biotechnologie, Belgium
  3. Mayo Clinic, USA
  4. Universität Würzburg, Germany
  5. University College London, UK
  6. Queen Mary University of London, UK
  7. Ruhr-Universität Bochum, Germany
  8. Physiologisches Institut der Universität Würzburg, Germany
  9. University of Minnesota, USA
  10. Ruhr University Bochum, Germany
  11. Maastricht University, The Netherlands
  12. Bayer AG, Germany
  13. Thomas Jefferson University, USA


Abstract

The mammalian genome encodes transmembrane and soluble receptor guanylyl cyclases, both of which have enzyme activities which convert guanosine-5'-triphosphate to the intracellular second messenger cyclic guanosine-3',5'-monophosphate (cyclic GMP).

Contents

This is a citation summary for Receptor guanylyl cyclase (RGC) family in the Guide to Pharmacology database (GtoPdb). It exists purely as an adjunct to the database to facilitate the recognition of citations to and from the database by citation analyzers. Readers will almost certainly want to visit the relevant sections of the database which are given here under database links.

GtoPdb is an expert-driven guide to pharmacological targets and the substances that act on them. GtoPdb is a reference work which is most usefully represented as an on-line database. As in any publication this work should be appropriately cited, and the papers it cites should also be recognized. This document provides a citation for the relevant parts of the database, and also provides a reference list for the research cited by those parts.

Please note that the database version for the citations given in GtoPdb are to the most recent preceding version in which the family or its subfamilies and targets were substantially changed. The links below are to the current version. If you need to consult the cited version, rather than the most recent version, please contact the GtoPdb curators.

Database links

Receptor guanylyl cyclase (RGC) family
http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=1022
    Transmembrane guanylyl cyclases
    http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=662
        Receptors
                GC-A(Guanylyl cyclase-A)
                http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1747
                GC-B(Guanylyl cyclase-B)
                http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1748
                GC-C(Guanylyl cyclase-C)
                http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1750
                NPR-C(natriuretic peptide receptor 3)
                http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1749
                GC-D(Guanylyl cyclase-D)
                http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2898
                GC-E(Guanylyl cyclase-E)
                http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2031
                GC-F(Guanylyl cyclase-F)
                http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2899
                GC-G(Guanylyl cyclase-G)
                http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2900
    Nitric oxide (NO)-sensitive (soluble) guanylyl cyclase
    http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=939
        Receptors
            Complexes
                GC-1(Guanylyl cyclase, α1β1)
                http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1287
                GC-2(Guanylyl cyclase, α2β1)
                http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2897
            Receptors and Subunits
                Guanylyl cyclase α1 subunit
                http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1288
                Guanylyl cyclase α2 subunit
                http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1289
                Guanylyl cyclase β1 subunit
                http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1290
                Guanylyl cyclase β2 subunit
                http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1291

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