IUPHAR/BPS Guide to Pharmacology CITE

Melanin-concentrating hormone receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

Valérie Audinot1, Jean A. Boutin2, Bernard Lakaye3, Jean-Louis Nahon4 and Yumito Saito5
  1. Institut de recherches Servier, France
  2. Institut de Recherches Internationales Servier, France
  3. University of Liège, Belgium
  4. CNRS Sophia Antipolis, France
  5. Hiroshima University, Japan


Melanin-concentrating hormone (MCH) receptors (provisional nomenclature as recommended by NC-IUPHAR [31]) are activated by an endogenous nonadecameric cyclic peptide identical in humans and rats (DFDMLRCMLGRVYRPCWQV; mammalian MCH) generated from a precursor (PMCH, P20382), which also produces neuropeptide EI and neuropeptide GE.


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Database links

Melanin-concentrating hormone receptors
Introduction to Melanin-concentrating hormone receptors
            MCH1 receptor
            MCH2 receptor


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